Acute cellular rejection in lung transplantation
نویسندگان
چکیده
منابع مشابه
Acute antibody-mediated rejection after lung transplantation.
BACKGROUND Antibody-mediated rejection (AMR) after lung transplantation remains enigmatic, and there is no consensus on the characteristic clinical, immunologic and histologic features. METHODS We performed a retrospective, single-center cohort study and identified cases of acute AMR based on the presence of circulating donor-specific human leukocyte antigen (HLA) antibodies (DSA), histologic...
متن کاملInterobserver variability in grading acute rejection after lung transplantation.
Affi liations: From the Department of Internal Medicine (Dr A. E. Mirrakhimov), Saint Joseph Hospital; and the Kyrgyz State Medical Academy (Dr E. A. Mirrakhimov). Financial/nonfi nancial disclosures: The authors have reported to CHEST that no potential confl icts of interest exist with any companies/organizations whose products or services may be discussed in this article . Correspondence to: ...
متن کاملAerosol cyclosporine prevents acute allograft rejection in experimental lung transplantation.
BACKGROUND The incidence of acute rejection and the morbidity of systemic cyclosporine (INN: cyclosporine) after lung transplantation is significant. Experimental evidence suggests that the allograft locally modulates the immune mechanisms of acute rejection. The purpose of this study was to determine whether aerosolized cyclosporine would prevent acute cellular rejection, achieve effective gra...
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How does the body recognize the donor lung as different? Your body’s natural immune cells are able to recognize small, unique proteins called “antigens” that are present on the surface of all cells or infectious particles. These immune cells, called the T cells and the B cells, can recognize the antigens as “self” if they belong to you or “non-self” if they do not belong to you (such as those i...
متن کاملLung rejection after transplantation.
With the introduction of Cyclosporine as an immunosuppressive agent, combined heart and lung transplantation (HLTx) became an effective treatment for severe pulmonary vascular disease [1] and has been extended successfully to treat end-stage lung disease [2] and cystic fibrosis [3, 4]. Single lung transplantation offers a treatment for cryptogenic fibrosing alveolitis [5]. It was initially beli...
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ژورنال
عنوان ژورنال: African Journal of Thoracic and Critical Care Medicine
سال: 2019
ISSN: 2617-0205,2617-0191
DOI: 10.7196/sarj.2019.v25i2.010